Methyl 2,3-dihydrobenzo[b]furan-5-carboxylate

Methyl 2,3-dihydrobenzo[b]furan-5-carboxylate - Names and Identifiers

Name	Methyl 2,3-dihydrobenzo[b]furan-5-carboxylate
Synonyms	Methyl2,3-Dihydro-benzofuran-5-carboxylate Methyl 2,3-dihydrobenzo[b]furan-5-carboxylate methyl 2,3-dihydro-1-benzofuran-5-carboxylate 2,3-Dihydro-5-benzofurancarboxylic acid Methyl ester 5-Benzofurancarboxylic acid, 2,3-dihydro-, Methyl ester
CAS	588702-80-1

Methyl 2,3-dihydrobenzo[b]furan-5-carboxylate - Physico-chemical Properties

Molecular Formula	C10H10O3
Molar Mass	178.18
Density	1.208±0.06 g/cm3(Predicted)
Boling Point	296.2±19.0 °C(Predicted)
Storage Condition	2-8°C
Sensitive	Irritant
MDL	MFCD00114411

Methyl 2,3-dihydrobenzo[b]furan-5-carboxylate - Introduction

Methyl 2,3-dihydrobenzo [B] furan-5-carboxylate is an organic compound with the chemical formula C11H10O3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Methyl 2,3-dihydrobenzo [B] furan-5-carboxylate is a colorless or pale yellow liquid.
-Melting point: about -15 ℃
-Boiling point: about 280 ℃
-Density: approx. 1.23g/cm³
-Soluble: Soluble in ethanol, ether and dichloromethane, almost insoluble in water.

Use:
- Methyl 2,3-dihydrobenzo [B] furan-5-carboxylate can be used as an intermediate in organic synthesis and is often used in the synthesis of other organic compounds.
-It is also used in the pharmaceutical field for the synthesis of drugs or pharmaceutical intermediates.

Preparation Method:
Methyl 2,3-dihydrobenzo [B] furan-5-carboxylate can be prepared by the following methods:
-First, 2-chlorophenol is reacted with potassium propionate to obtain 2-propionylphenol.
-Then, through an esterification reaction, 2-propionylphenol is reacted with methanol to generate 2-propionylphenyl methyl ester.
-Finally, 2-propionylphenyl methyl ester is subjected to a reductive cycloaddition reaction to generate Methyl 2,3-dihydrobenzo [B] furan-5-carboxylate.

Safety Information:
- Methyl 2,3-dihydrobenzo [B] furan-5-carboxylate may be irritating to the skin, eyes and respiratory tract and should be rinsed with plenty of water immediately after contact.
-use and storage, should avoid contact with oxidants, acids, alkalis and other substances, to prevent unsafe reaction.
-During use, care should be taken to comply with laboratory safety procedures and wear appropriate personal protective equipment (such as gloves, glasses and protective clothing).

Last Update：2024-04-09 21:01:54